Very little is known about Canning, other than she became an FBI agent. By the events of "Gabby", she was working in a high position in the FBI's Mississippi field office. She has commonly assisted the BAU during cases involving child abductions and human trafficking.
Canning was one of the investigators assisting the BAU in tracking down four-year-old Gabby Hoffer, who mysteriously disappeared while staying with Sue Walsh, a relative. The agents initially believe it is the work of Gabby's estranged father Doug. However, their viewpoint of the case changes when they find Doug dead and they shift their focus to Sue herself. Through extensive interrogations, Canning and the BAU realize Sue arranged for Gabby to be abducted and given away via "disrupted adoption", an emerging criminal business in the U.S. They eventually find Gabby and two other children being held captive by Michelle Fader, a woman previously convicted of criminal negligence involving children, and Michael Feehan, a known pedophile.
She later assists the BAU in tracking down Meg Callahan and Markayla Davis when they are abducted by a man posing as a teenage boy. As the investigation proceeds, they realize that Meg and Markayla are the latest victims of a human trafficking ring that caters to serial killers and the like. Canning and the other BAU agents help provide a profile of the ring to local police officers and reporters. By the end of the episode, the team is able to safely retrieve both children.