- Toneey Acevedo - Homeless Man #1
- John Cothran, Jr. - Trooper Jim Carson
- Rick Cramer - Curtis Burton
- Chrisanne Eastwood - M.E. Patricia Olwyler
- Courtney Gains - Todd Burton
- Parker C. Hix - Young Todd Burton
- Luke Judy - Young Cormac Burton
- Jake O'Flaherty - Colin Maynard
- Afsheen Olyaie - Sheriff's Deputy
- Tripp Pickell - Howard Walker
- David Schroeder - Tom Covington
- Dusty Sorg - Cormac Burton
- Luke Alvez: A Cheyenne proverb says, "Beware the man who does not talk and the dog that does not bark."
- Spencer Reid: "What greater thing is there for human souls than to feel that they are joined for life, to be with each other in silent unspeakable memories?" – George Eliot
- The episode was initially set to be directed by Thomas Gibson, the actor portraying Aaron Hotchner, but he was replaced following an altercation on the set with writer/producer Virgil Williams, for which he was temporarily suspended and then dismissed from the show.
- Dusty Sorg, the actor portraying Cormac Burton, had previously portrayed Vernon Butts, the accomplice to real-life serial killer and rapist William Bonin, in the 2010 film Freeway Killer.
- Tripp Pickell, the actor portraying Howard Walker, previously appeared in the Season One episode "Won't Get Fooled Again", in which he portrayed a bomb technician.
- Afsheen Olyaie, the actor portraying a Sheriff's Deputy, also separately played a slumdog and a Casablanca police officer in two episodes of Beyond Borders.