When a family of four is abducted while on vacation in Barbados, and the case is connected to several others, including one they investigated last year in Florida, Hotch and the BAU are called in to assist Unit Chief Jack Garrett and his International Response Team, which specializes in cases that involve Americans staying abroad, in a joint investigation.
- Newell Alexander - Joe Sullivan
- Sterling K. Brown - Fitz
- Maritza Cabrera - Assistant Alisha Paun
- Dylan Garza - Young Jerry Tidwell
- Gatlin Green - Alison Sullivan
- Anna Gunn - Agent Lily Lambert
- Daniel Henney - Agent Matthew Simmons
- Darri Ingolfsson - Jerry Tidwell
- Shawn Kyles - Mr. Tidwell
- Lu Louis - Local Driver
- Judith McConnell - Pat Sullivan
- Jakob and Andrew Miller - Nick Sullivan
- Sara Montez - Charlotte Keller
- Esai Morales - FBI Section Chief Director Mateo Cruz
- Jami Platt - Mrs. Tidwell
- Tom Everett Scott - Greg Sullivan
- Gary Sinise - Unit Chief Jack Garrett
- Bonnie Somerville - Colleen Sullivan
- Tyler James Williams - Analyst Russ Montgomery
- Joran van der Sloot and the Natalee Holloway case
- "Sleep Peacefully" by Lily Kershaw
- Aaron Hotchner: "No matter how fast light travels, it finds the darkness is always there first." Terry Pratchett
- Jack Garrett: "Coming together is a beginning; keeping together is progress; working together is success." Henry Ford
- This episode is the backdoor pilot episode of the new proposed spin-off series, titled Criminal Minds: Beyond Borders.
- A similar version of the opening bookend quote recited by Hotch was recited by Reid in the Season Four episode Conflicted.
- This episode marks the third time the BAU have gone to another country to investigate a case. The first time was in Machismo, which had the BAU go to Mexico, and the second time was in the two-part episode To Hell...and Back, which had the BAU go to Canada.