The BAU hunts an unsub in Phoenix who is abducting victims and depriving them of their sleep. Also, Hotch and Garcia deal with the threat from an underground hitman group who have targeted the Dirty Dozen, a name Garcia realizes they are using to refer to her.
- Akira Akbar - Daughter
- Sandy Bainum - Karen Coleman
- Guile Branco - Stephen Jackson
- Tommy Dickie - Manager
- Leah Garland - Doctor Pat Lewis
- Troy Jones - Skull Tattoo Man
- Lexy Kolker - Tatiana Taylor
- William Langan - Lance Coleman
- Todd Lowe - William Taylor
- James Morosini - David Whitfield
- Aisha Tyler - Doctor Tara Lewis
- Gloria Votsis - Agent Debbie Webster
- Danette Wilson - Mother
- "You Are My Sunshine" by Leah Andreone
- Jennifer Jareau: "You can chain me, you can torture me, you can even destroy this body, but you will never imprison my mind." — Mahatma Gandhi
- Jennifer Jareau: "Guilt is perhaps the most painful companion of death." — Coco Chanel
- Despite being credited in the opening sequence, Matthew Gray Gubler, the actor who portrays Reid, doesn't appear in the episode and is only mentioned.
- This is, in fact, the third episode in which a main character has not appeared despite his or her actor or actress being credited as usual. The first episode was Broken Mirror, in which A.J. Cook and Kirsten Vangsness do not appear as JJ and Garcia, respectively, despite being credited. The second was 25 to Life, in which Thomas Gibson does not appear as Hotch.
- ↑ Credited as "Woman"