- Lily Berlina - Madison Mills
- Andrea Bordeaux - Kelly Goodwin
- Laura Breckenridge - Nicole Seavers
- Ava Browne - Young Dana Seavers
- Brooke Coleman - Brandy Greene
- Sheila Cutchlow - M.E. Juliette Raynard
- Ashley Fink - Dana Seavers
- Aaron Gaffey - Karl Ulrich
- Michael Irvin - Himself
- Punnavith Koy - Police Detective
- Derek Morgan - Captain Beau Hallendale
- Mancow Muller - Disc Jockey
- Jamie Owen - Ashley Wilcox
- Dominic Pace - Bouncer
- David Paetkau - Ryan Becker
- Maxie Santillan, Jr. - Homeless Man
- Aisha Tyler - Doctor Tara Lewis
- "I'm Gone Mama" by Jim Murphy and The Accents
- "There He (She) Goes (Absent)" (Original by Neve) by Gia Mantegna
- Tara Lewis: "And think not that you can direct the course of love, for love, if it finds you worthy, directs your course." – Khalil Gibran's The Prophet
- David Rossi: Alfred Lord Tennyson wrote, "I hold it true, whate'er befall; I feel it, when I sorrow most; 'Tis better to have loved and lost than never to have loved at all."
- Derek Morgan (actor) previously costarred with Joe Mantegna in multiple episodes of Joan of Arcadia after starring as Thomas Gibson on For the People.
- ↑ Credited as "NFL Player"